Fibroblast growth factor 23 and cognitive impairment: The health, aging, and body composition study

Fibroblast growth factor 23 and cognitive impairment: The health, aging, and body composition study

Background: Fibroblast growth factor (FGF-23) concentration, a hormone that governs the phosphorus and the metabolism of vitamin D, increase as a renal function decreases. The excess fibroblast growth factor can affect cerebral function by promoting vascular disease or direct effects on neuronal tissues.
Methods: In the aging of health and a body composition study, a longitudinal observation cohort of well-functioning seniors, the Intact FGF-23 serum was analyzed in 2,738 people. The cognitive function was evaluated at the base of reference and longitudinally to the years 3, 5 and 8 by the administration of the modified mini-state examination (3MSE), a global cognitive function test and the substitution test of the Digital symbols (DSST), a primarily executive function test. Associations between FGF-23 and the cognitive cognitive function and a cognitive impairment incident have been evaluated using the logistic and fish regression respectively and have been adjusted for demographic data, the estimated glomerular filtration rate (EGFR), urine albumin / creatinine, comorbidity and other mineral metabolism measures, including Klotho soluble.

Results: Average age (SD) was 74 (3) years, with 51% women and 39% black. The median concentration (25th 75e) FGF-23 was 47 pg / ml (37, 60). Three hundred and ninety-two people had a cognitive impairment prevalent by 3MSE and 461 by the DSST. There was no observed association between FGF-23 and the basic cognitive function for a cognitive test. There were 277 people with an incident cognitive impairment of 3mse and 333 people with an incident cognitive impairment of the DSST. In fully adjusted models, each two-time Basic FGF-23 concentration has not been associated with a cognitive impaired deficiency by the 3MSE model (IRR = 1.02 [0.88, 1.19] fully adjusted) or by The DSST (IRR = 0.98 [0.84, 1.15]. We have not seen any difference when analyzes have been laminated by EGFR greater than or less than 60 ml / min / 1.73m2.

 

Post-translation modification faults in fibroblast growth factor receptor 1 due to the reason for normosmic isolated hypogonadotropic hypogonadism

Some mutations of FGFR1 affect the sense of smell while others do not, resulting in Kallmann syndrome (KS) and hypogonadotropic hypogonadism isolated from normosmic (NiHH), respectively. The underlying mechanism is still unclear. The FGFR1 variants are in less than 10% of patients with KS and NIHH, and among them, only some have undergone functional analysis. Thus, the correlation between the phenotype and the genotype can not be clearly checked. This study reports a case of Nihh and explores the potential mechanism of the FGFR1 gene in the pathogenesis of NIHH. A preschool child with cryptorchidism, micropenis, strabismus and hypotgie is described. As he had a sense of normal smell, he was diagnosed with Nihh. A mutation of NOVO in FGFR1 (C.2008G> A) was detected in the patient with a new variant at CEP290 (C.964G> A) inherited from his mother.

We present convincing in vitro evidence that this post-procedure modification defect induced by the FGFR1 mutations, including defective glycosylation and altered trans-autophosphorylation, as well as the final reduction of the expression, could result in a disability of the receiver and abnormal signage and ultimately lead to development anomalies and inhibition of GNRH neuron release. The identification of an additional variant suggests that the CEP290 could play a potential role in the development of GNRH. We have examined here the role of PTEN (Phosphatase and Tensin Homology removed from chromosome 10) in this Regulation. We have created devoid mice of Pten Expression mainly in osteocytes crossing Pten-Flox mice with DMP1-CRE mice. The absence of PTEN in the osteocytes of these mice was associated with the decrease in the levels of skeletal and serum FGF23, which, in turn, resulted in a reduction in the excretion of urinaryi and elevations of serum pi levels. .

Fibroblast growth factor 23 and cognitive impairment: The health, aging, and body composition study
Fibroblast growth factor 23 and cognitive impairment: The health, aging, and body composition study

Fibroblast Growth Factor Receivers in Cancer: Genetic Alterations, Diagnostics, Therapeutic Targets and Resistance Mechanisms

Fibroblast growth factor (FGFRS) receptors are activated abandally activated by monocleotide variants, gene mergers and copy number amplifications in 5 to 10% of all human cancer, although this frequency increases to 10- 30% in urothelial carcinoma and intrahepatic cholangiocarcinoma. We begin this review by highlighting the diversity of FGFR genomic modifications identified in human cancer and current challenges associated with the development of clinical quality molecular diagnostic tests for accurately detecting these changes in patients’ tissue and blood. The last decade has experienced significant progress in the development of FGFR targeted therapies, which include selective, non-selective and covalent molecule covalent inhibitors, as well as monoclonal antibodies against receptors.

We describe the expanding landscape of anti-FGFR therapies that are evaluated in early phase and randomized controlled clinical trials, such as Erdifineib and Pemigatinib, which are approved by the Food and Medicine Administration for the treatment of carcinoma. Urothelial mutated of the FGFR3 and FGFR2-Cholangiocarcinoma Fusion, respectively. However, despite the initial sensitivity to the inhibition of the FGFR, the drug resistance acquired to the progression of cancer develops in most patients. This phenomenon emphasizes the need to clearly define the mechanisms of resistance of tumor tumors and extrinsic tumor to facilitate the development of second-generation FGFR inhibitors and new treatment strategies beyond the progression of targeted therapy.

 

FGF-1 Fibroblast Growth Factor-Acidic Human Recombinant Protein, Sf9

PROTP05230-1 Regular: 10ug
EUR 380.4
Description: Fibroblast Growth Factor-1 Human Recombinant (FGF-1) produced in Sf9 insect cells is a single, glycosylated, polypeptide chain containing 140 amino acids and having a molecular mass of 15803 Dalton. ;The FGF-a is purified by proprietary chromatographic techniques.

FGF4 Fibroblast Growth Factor-4 Human Recombinant Protein

PROTP08620-1 Regular: 25ug
EUR 380.4
Description: FGF4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 182 amino acids and having a molecular mass of 19.8kDa. ;The FGF4 is purified by proprietary chromatographic techniques.

FGF17 Fibroblast Growth Factor 17 Human Recombinant Protein

PROTO60258-1 Regular: 25ug
EUR 380.4
Description: FGF17 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 195 amino acids and having a molecular mass of 22.6kDa. 

FGF-2 Fibroblast Growth Factor Basic Bovine protein

PROTP03969-1 Regular: 5ug
EUR 429.6
Description: FGF-2 Bovine purified from bovine pituitary is a single, glycosylated, polypeptide chain having a molecular mass of 16kDa.;The basic-FGF is purified by proprietary chromatographic techniques.

Anti-Fibroblast growth factor 21 antibody

STJ71323 100 µg
EUR 430.8

Human Fibroblast growth factor receptor 1 (FGFR1)

1-CSB-EP008642HU1
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor receptor 1(FGFR1),partial expressed in E.coli

Human Fibroblast growth factor receptor 1 (FGFR1)

1-CSB-EP008642HUa0
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor receptor 1(FGFR1),partial expressed in E.coli

Human Fibroblast growth factor receptor 1 (FGFR1)

1-CSB-YP008642HUa4
  • EUR 516.00
  • EUR 280.80
  • EUR 1809.60
  • EUR 770.40
  • EUR 1210.80
  • EUR 349.20
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor receptor 1(FGFR1),partial expressed in Yeast

FGF-21 Fibroblast Growth Factor-21 Human Recombinant Protein

PROTQ9NSA1-1 Regular: 25ug
EUR 380.4
Description: Fibroblast Growth Factor -21 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 182 amino acids and an N-terminal Methionin (bold), having a molecular weight of 19.5 kDa. ;The FGF-21 is purified by proprietary chromatographic techniques.

FGF-8 Fibroblast Growth Factor-8 Human Recombinant Protein

PROTP55075-1 Regular: 25ug
EUR 380.4
Description: FGF 8 Human Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 194 amino acids and having a total molecular mass of 22.5kDa. 

FGF-19 Fibroblast Growth Factor-19 Human Recombinant Protein

PROTO95750-1 Regular: 25ug
EUR 380.4
Description: FGF19 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 195 amino acids and having a molecular mass of 21.8 kDa.;The FGF-19 is purified by proprietary chromatographic techniques.

Fibroblast growth factor 1 Polyclonal Antibody

42169-100ul 100ul
EUR 399.6

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx109783
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx109784
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx112524
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx000547
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx000820
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Fibroblast Growth Factor 1 (FGF1) Antibody

abx233087-100ug 100 ug
EUR 610.8

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx320141
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx322141
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx326446
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx214480
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Fibroblast Growth Factor 1 (FGF1) Antibody

20-abx214934
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Human Fibroblast Growth Factor 12 (FGF-12) AssayMax ELISA Kit

EF2521-1 96 Well Plate
EUR 500.4

Human Fibroblast Growth Factor 21 (FGF-21) AssayMax ELISA Kit

EF3021-1 96 Well Plate
EUR 500.4

FGF-2 Fibroblast Growth Factor-Basic Human Recombinant Protein, Plant

PROTP09038-1 Regular: 50ug
EUR 380.4
Description: FGF-2 Human Recombinant produced in rice is a single, non-glycosylated polypeptide chain containing 146 amino acids and having a molecular mass of ~17kDa.;The FGF-b protein is purified by proprietary chromatographic techniques.

FGFR2 Fibroblast Growth Factor Receptor 2 Fc ChimeraHuman Recombinant Protein

PROTP21802-1 Regular: 10ug
EUR 380.4
Description: Soluble FGFR-2a (IIIc) Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric, glycosylated, Polypeptide chain and having a molecular mass of 195 kDa. ;The FGFR2 is purified by proprietary chromatographic techniques.

Human Fibroblast growth factor 10 (FGF10)

1-CSB-EP008616HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 10(FGF10) expressed in E.coli

Human Fibroblast growth factor 12 (FGF12)

1-CSB-EP008618HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 12(FGF12) expressed in E.coli

Human Fibroblast growth factor 13 (FGF13)

1-CSB-EP008619HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 13(FGF13) expressed in E.coli

Human Fibroblast growth factor 14 (FGF14)

1-CSB-EP008620HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 14(FGF14) expressed in E.coli

Human Fibroblast growth factor 2 (FGF2)

1-CSB-EP008625HUa2
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 2(FGF2) expressed in E.coli

Mouse Fibroblast growth factor 21 (Fgf21)

1-CSB-EP008627MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Fibroblast growth factor 21(Fgf21) expressed in E.coli

Rat Fibroblast growth factor 23 (Fgf23)

1-CSB-EP008629RA
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Fibroblast growth factor 23(Fgf23) expressed in E.coli

Human Fibroblast growth factor 2 (FGF2)

1-CSB-YP008625HU
  • EUR 604.80
  • EUR 318.00
  • EUR 2198.40
  • EUR 915.60
  • EUR 1459.20
  • EUR 400.80
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 2(FGF2) expressed in Yeast

Rat Fibroblast growth factor 23 (Fgf23)

1-CSB-YP008629RA
  • EUR 604.80
  • EUR 318.00
  • EUR 2198.40
  • EUR 915.60
  • EUR 1459.20
  • EUR 400.80
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Fibroblast growth factor 23(Fgf23) expressed in Yeast

Mouse Fibroblast growth factor 15 (Fgf15)

1-CSB-EP522052MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Fibroblast growth factor 15(Fgf15) expressed in E.coli

Human Fibroblast growth factor 10 (FGF10)

1-CSB-EP008616HU(F1)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 10(FGF10),partial expressed in E.coli

Human Fibroblast growth factor 10 (FGF10)

1-CSB-EP008616HU(F2)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Fibroblast growth factor 10(FGF10),partial expressed in E.coli

FGF-21 Fibroblast Growth Factor-21 Mouse Recombinant Protein, His Tag

PROTQ9JJN1-1 Regular: 10ug
EUR 380.4
Description: Fibroblast Growth Factor -21 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 192 amino acids and having a molecular mass of 21.2 kDa. The amino acid sequence of the recombinant human FGF21 is 100% homologous to the amino acid sequence of the Mouse FGF21 without signal sequence and contains 10 a.a. His tag at N-terminal.;The FGF-21 is purified by proprietary chromatographic techniques.

FGFR4 Fibroblast Growth Factor Receptor 4 Fc Chimera Human Recombinant Protein

PROTP22455-1 Regular: 10ug
EUR 380.4
Description: Soluble FGFR-4a (IIIc) Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric, glycosylated, Polypeptide chain and having a molecular mass of 170 kDa. ;The FGFR4 is purified by proprietary chromatographic techniques.

FGF-8 Fibroblast Growth Factor-8 Mouse Recombinant Protein, 194 a.a.

PROTP37237-1 Regular: 25ug
EUR 380.4
Description: FGF 8 Mouse Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 194 amino acids and having a total molecular mass of 22.5kDa. 

FGF-18 Fibroblast Growth Factor-18 Human Recombinant Protein, His Tag

PROTO76093-1 Regular: 10ug
EUR 380.4
Description: FGF18 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (Glu28-Ala207) containing 190 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 22.3kDa.

Rabbit Fibroblast growth factor 16

ERTF0077 96Tests
EUR 625.2

Bovine Fibroblast Growth Factor-acidic

7-00328 1µg Ask for price

Bovine Fibroblast Growth Factor-acidic

7-00329 5µg Ask for price

Bovine Fibroblast Growth Factor-acidic

7-00330 100µg Ask for price

Bovine Fibroblast Growth Factor-basic

7-00343 2µg Ask for price

Bovine Fibroblast Growth Factor-basic

7-00344 5µg Ask for price

Bovine Fibroblast Growth Factor-basic

7-00345 10µg Ask for price

Fibroblast Growth Factor Basic Antibody

20-abx137007
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Fibroblast Growth Factor-basic Protein

20-abx260405
  • EUR 627.60
  • EUR 360.00
  • EUR 477.60
  • 10 ug
  • 2 µg
  • 5 ug

Fibroblast Growth Factor-21 Protein

20-abx260473
  • EUR 276.00
  • EUR 2798.40
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-acidic Protein

20-abx260700
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Fibroblast Growth Factor 13 Protein

20-abx260704
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-4 Protein

20-abx260720
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-19 Protein

20-abx260746
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor 17 Protein

20-abx260755
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor 17 Protein

20-abx260773
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-18 Protein

20-abx261616
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-8 Protein

20-abx261618
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-21 Protein

20-abx261622
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Fibroblast Growth Factor-18 Protein

20-abx261631
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-21 Protein

20-abx261656
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-8 Protein

20-abx261694
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-23 Protein

20-abx261809
  • EUR 5254.80
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Fibroblast Growth Factor-9 Protein

20-abx261823
  • EUR 393.60
  • EUR 5254.80
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor-9 Protein

20-abx261826
  • EUR 5254.80
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Fibroblast Growth Factor-9 Protein

20-abx261829
  • EUR 393.60
  • EUR 5254.80
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor-21 Protein

20-abx262037
  • EUR 393.60
  • EUR 5388.00
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor-19 Protein

20-abx262135
  • EUR 6273.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Fibroblast Growth Factor-15 Protein

20-abx262361
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor 12 Protein

20-abx262397
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor 14 Protein

20-abx262406
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor-21 Protein

20-abx262988
  • EUR 393.60
  • EUR 8010.00
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor-22 Protein

20-abx263030
  • EUR 393.60
  • EUR 8829.60
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Fibroblast Growth Factor-basic Protein

20-abx263078
  • EUR 276.00
  • EUR 1245.60
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-basic Protein

20-abx263178
  • EUR 276.00
  • EUR 1746.00
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-23 Protein

20-abx263244
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

Fibroblast Growth Factor-basic Protein

20-abx263467
  • EUR 276.00
  • EUR 2013.60
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-basic Protein

20-abx263468
  • EUR 276.00
  • EUR 2013.60
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-basic Protein

20-abx263469
  • EUR 276.00
  • EUR 2013.60
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-acidic Protein

20-abx263498
  • EUR 276.00
  • EUR 2148.00
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-acidic Protein

20-abx263501
  • EUR 276.00
  • EUR 2148.00
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast Growth Factor-acidic Protein

20-abx263504
  • EUR 276.00
  • EUR 2148.00
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Fibroblast growth factor 10/FGF10

E21-R11 10ug
EUR 411.6

Human acidic Fibroblast Growth Factor

90101-A 10 µg
EUR 130
Description: Recombinant human aFGF (acidic Fibroblast Growth Factor) is a disulfide-linked monomer protein consisting of 141 a.a. and migrates as an approximately 16 kDa protein under reducing and non-reducing conditions. Native human aFGF, generated by the proteolytic removal of the signal peptide and propeptide, has a calculated mass of 16 kDa. Optimized DNA sequence encoding human acidic Fibroblast Growth Factor mature chain was expressed in E. coli.

Human acidic Fibroblast Growth Factor

90101-B 50 µg
EUR 205
Description: Recombinant human aFGF (acidic Fibroblast Growth Factor) is a disulfide-linked monomer protein consisting of 141 a.a. and migrates as an approximately 16 kDa protein under reducing and non-reducing conditions. Native human aFGF, generated by the proteolytic removal of the signal peptide and propeptide, has a calculated mass of 16 kDa. Optimized DNA sequence encoding human acidic Fibroblast Growth Factor mature chain was expressed in E. coli.

Mouse acidic Fibroblast Growth Factor

90102-A 10 µg
EUR 130
Description: Recombinant murine aFGF (acidic Fibroblast Growth Factor) is a disulfide-linked monomer protein consisting of 141 a.a. and migrates as an approximately 16 kDa protein under reducing and non-reducing conditions. Native murine aFGF, generated by the proteolytic removal of the signal peptide and propeptide, has a calculated mass of 16 kDa. Optimized DNA sequence encoding murine acidic Fibroblast Growth Factor mature chain was expressed in E. coli.

Mouse acidic Fibroblast Growth Factor

90102-B 50 µg
EUR 205
Description: Recombinant murine aFGF (acidic Fibroblast Growth Factor) is a disulfide-linked monomer protein consisting of 141 a.a. and migrates as an approximately 16 kDa protein under reducing and non-reducing conditions. Native murine aFGF, generated by the proteolytic removal of the signal peptide and propeptide, has a calculated mass of 16 kDa. Optimized DNA sequence encoding murine acidic Fibroblast Growth Factor mature chain was expressed in E. coli.

Mouse basic Fibroblast Growth Factor

90112-A 10 µg
EUR 130
Description: Recombinant mouse bFGF is a disulfide-linked homodimeric protein consisting of 146 amino acid residue subunits, and migrates as an approximately 16 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Mouse basic Fibroblast Growth Factor mature chain was expressed in E. coli.

Mouse basic Fibroblast Growth Factor

90112-B 50 µg
EUR 205
Description: Recombinant mouse bFGF is a disulfide-linked homodimeric protein consisting of 146 amino acid residue subunits, and migrates as an approximately 16 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Mouse basic Fibroblast Growth Factor mature chain was expressed in E. coli.

Human Fibroblast Growth Factor 10

90133-A 5 µg
EUR 130
Description: Recombinant human FGF-10, (Fibroblast Growth Factor 10), is a disulfide-linked monomer protein consisting of 169 amino acids and migrates as an approximately 19 kDa protein under reducing and non-reducing conditions. Source: Optimized DNA sequence encoding human FGF-10 mature chain was expressed in E. coli.

Human Fibroblast Growth Factor 10

90133-B 25 µg
EUR 205
Description: Recombinant human FGF-10, (Fibroblast Growth Factor 10), is a disulfide-linked monomer protein consisting of 169 amino acids and migrates as an approximately 19 kDa protein under reducing and non-reducing conditions. Source: Optimized DNA sequence encoding human FGF-10 mature chain was expressed in E. coli.

Human Fibroblast Growth Factor 21

90134-A 5 µg
EUR 130
Description: Recombinant Fibroblast Growth Factor 21 is a disulfide-linked monomer protein consisting of 182 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Fibroblast Growth Factor-21 mature chain was expressed in E. coli.

Human Fibroblast Growth Factor 21

90134-B 20 µg
EUR 205
Description: Recombinant Fibroblast Growth Factor 21 is a disulfide-linked monomer protein consisting of 182 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Fibroblast Growth Factor-21 mature chain was expressed in E. coli.

Human Fibroblast Growth Factor-9

90135-A 5 µg
EUR 130
Description: Recombinant Fibroblast Growth Factor-9 is a disulfide-linked monomer protein consisting of 208 amino acid residues, and migrates as an approximately 23 kDa protein under non-reducing and reducing conditions in SDS-PAGE.

Human Fibroblast Growth Factor-9

90135-B 20 µg
EUR 205
Description: Recombinant Fibroblast Growth Factor-9 is a disulfide-linked monomer protein consisting of 208 amino acid residues, and migrates as an approximately 23 kDa protein under non-reducing and reducing conditions in SDS-PAGE.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Fibroblast growth factor 1 Polyclonal Conjugated Antibody

C42169 100ul
EUR 476.4

Recombinant Human Fibroblast Growth Factor Receptor-1

7-03958 2µg Ask for price

Recombinant Human Fibroblast Growth Factor Receptor-1

7-03959 10µg Ask for price

Recombinant Human Fibroblast Growth Factor Receptor-1

7-03960 1mg Ask for price

Fibroblast Growth Factor 1 (FGF1) Antibody (HRP)

20-abx108252
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody (HRP)

20-abx108253
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx103824
  • EUR 360.00
  • EUR 159.60
  • EUR 944.40
  • EUR 493.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx103825
  • EUR 393.60
  • EUR 978.00
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody (Biotin)

20-abx105414
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody (Biotin)

20-abx105415
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody (FITC)

20-abx106833
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1 (FGF1) Antibody (FITC)

20-abx106834
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx103579
  • EUR 376.80
  • EUR 159.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx103580
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx103581
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx103582
  • EUR 543.60
  • EUR 159.60
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx172380
  • EUR 844.80
  • EUR 427.20
  • 1 mg
  • 200 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx172381
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx172382
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx172383
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx172384
  • EUR 1111.20
  • EUR 560.40
  • 1 mg
  • 200 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx172422
  • EUR 1045.20
  • EUR 543.60
  • 1 mg
  • 200 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx145184-100ug 100 ug
EUR 469.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx133072
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx117196-100ug 100 ug
EUR 560.4

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx130389
  • EUR 526.80
  • EUR 159.60
  • EUR 1496.40
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx130427
  • EUR 560.40
  • EUR 159.60
  • EUR 1646.40
  • EUR 777.60
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx131790
  • EUR 326.40
  • EUR 727.20
  • EUR 393.60
  • EUR 184.80
  • EUR 276.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx131859
  • EUR 393.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx007518
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx001688
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx011769-100ul 100 ul
EUR 493.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx012776
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Fibroblast Growth Factor Receptor 1 (Fgfr1) Antibody

abx028349-400ul 400 ul
EUR 627.6

Fibroblast Growth Factor Receptor 1 (Fgfr1) Antibody

abx028349-80l 80 µl
EUR 343.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033553-400ul 400 ul
EUR 627.6

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033553-80l 80 µl
EUR 343.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033554-400ul 400 ul
EUR 627.6

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033554-80l 80 µl
EUR 343.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033555-400ul 400 ul
EUR 627.6

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033555-80l 80 µl
EUR 343.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033556-400ul 400 ul
EUR 627.6

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033556-80l 80 µl
EUR 343.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033557-400ul 400 ul
EUR 627.6

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx033557-80l 80 µl
EUR 343.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx233099-100ug 100 ug
EUR 661.2

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx332211-100ul 100 ul
EUR 510

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx332387-100ul 100 ul
EUR 510

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx270120
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx431251-200ul 200 ul
EUR 460.8

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

abx432689-200ul 200 ul
EUR 460.8

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx302471
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx328127
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx328152
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Fibroblast Growth Factor Receptor 1 (FGFR1) Antibody

20-abx328975
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Fibroblast Growth Factor 1, Acidic (FGF1) Antibody

20-abx176394
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

 

The treatment of metastatic melanoma has changed dramatically over the past decade with the introduction of targeted immunotherapy and therapy. Futile disease in the past is now treated with various options, resulting in improved survivors without progression and global, as well as improving the quality of life.

April

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