Glucosamine impedes transforming growth factor β1-mediated corneal fibroblast differentiation by targeting Krüppel-like factor 4.

Glucosamine impedes transforming growth factor β1-mediated corneal fibroblast differentiation by targeting Krüppel-like factor 4.

Transforming growth factor (TGF) family members play an important role in the regulation of the integrity of the cornea, and the pathogenesis of fibrosis cornea. Currently, there are no effective agents targeting TGF-β signaling to reduce corneal fibrosis. Glucosamine (GlcN), which are widely used in the treatment of osteoarthritis, cancel the morphological effects of TGF-β2 in the cells of the retinal pigmented epithelium in disease model mice. Here, we sought to determine whether GlcN will provide beneficial effects on TGF-β1-induced corneal fibrosis.

In human corneal fibroblasts (HCF) is treated with GlcN, expression Krüppel-like factor 4 (KLF4) and downstream signaling effects specified in presence and absence of TGF-β1 using immunoblot analysis. We further explored GlcN inhibition of fibroblast-to-myofibroblast differentiation through KLF4 siRNA. Effect of cycloheximide on protein levels of KLF4 with or without the administration of GlcN assessed to determine whether KLF4 protein.In GlcN affect the stability of health-care facilities, GlcN induced expression of KLF4, which regulated the maturation and maintenance of the ocular surface.

GlcN partially suppress the expression of TGF-β1-induced alpha-smooth muscle actin (α-SMA) and reduced collagen contraction capacity in health care facilities, showed a decrease in fibroblast-to-myofibroblast differentiation. This effect appears to be mediated through suppression of Smad2 phosphorylation and ERK-dependent signaling. KLF4 mRNA level increased by GlcN and decreased TGF-β1 and TGF-β1-induced expression of α-SMA mRNA was upregulated when KLF4 genes silenced. GlcN also appeared to stabilize KLF4 protein, reduce turnover in the cornea fibroblasts.

These findings explain the mechanism of a novel by which GlcN suppress TGF-β1-induced fibroblast-to-myofibroblast differentiation through upregulation of KLF4 expression. current strategies for treating corneal fibrosis ineffective. Raised levels of KLF4 through the use of GlcN may provide an effective alternative to ease the development and progression of corneal fibrosis.

Glucosamine impedes transforming <em>growth</em> <em>factor</em> β1-mediated corneal <em>fibroblast</em> differentiation by targeting Krüppel-like <em>factor</em> <em>4</em>.
Glucosamine impedes transforming growth factor β1-mediated corneal fibroblast differentiation by targeting Krüppel-like factor 4.

Fibroblasts growth factor receptor 4 (FGFR 4 ) were detected by immunohistochemistry associated with postoperative residual disease in ovarian cancer.

Fibroblast Growth Factor Receptor 4 (FGFR4) proposed to hold prognostic significance in high-grade serous ovarian carcinoma (HGSOC). However, information about this comes from a large, representative patient panel is still missing, although such data would be necessary for compliance validation of FGFR4 as a prognostic marker or even a pharmacological target. 1063 cases of ovarian cancer were included in this study.

Immunohistochemistry (IHC) was performed using two different anti-FGFR4 specific antibody (HPA027273, sc-124) on the automated staining system. IHC data from two FGFR4 antibodies were available from 995 cases. FGFR4 immunostaining correlated with survival prognostic factors included using proportional hazards models uni and multivariate analyzes. FGFR4 positively associated with advanced FIGO stage, high grade and presence of residual disease.

p38 Antibody

48644-100ul 100ul
EUR 399.6

p38 Antibody

48644-50ul 50ul
EUR 286.8

p38 Antibody

35478-100ul 100ul
EUR 468

p38 Antibody

20-abx133223
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

20-abx141038
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

20-abx007541
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

abx236076-100ug 100 ug
EUR 577.2

p38 protein

E20-80078 20ug
EUR 489.6

p38 protein

E20-80079 20ug
EUR 489.6

anti-p38

YF-PA11120 50 ug
EUR 435.6
Description: Mouse polyclonal to p38

anti-p38

YF-PA11121 100 ug
EUR 483.6
Description: Rabbit polyclonal to p38

anti-p38

YF-PA23519 50 ul
EUR 400.8
Description: Mouse polyclonal to p38

anti-p38

YF-PA23520 50 ul
EUR 400.8
Description: Mouse polyclonal to p38

anti-p38

YF-PA23521 50 ul
EUR 400.8
Description: Mouse polyclonal to p38

MM-102

B2364-25
EUR 705.6

MM-102

B2364-5
EUR 222

PPQ-102

B3504-10 10 mg
EUR 290.4

PPQ-102

B3504-5 5 mg
EUR 181.2

PPQ-102

B3504-50 50 mg
EUR 1035.6

PM 102

B5517-1 1 mg
EUR 721.2

MM-102

B1582-2 2 mg
EUR 153.6
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase.

MM-102

B1582-20 20 mg
EUR 711.6
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase.

MM-102

B1582-5 5 mg
EUR 254.4
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase.

LSZ-102

HY-111486 50mg
EUR 3985.2

MM-102

HY-12220 10mg
EUR 357.6

IAXO-102

HY-125171 50mg
EUR 2332.8

PPQ-102

HY-14179 100mg
EUR 1465.2

BGB-102

HY-15732 10mg
EUR 7249.2

EL-102

HY-16187 10mM/1mL
EUR 451.2

5(6)-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9*

102 25 g
EUR 1051.2

SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor

E1B1863 1mg
EUR 193.2

p38 Polyclonal Antibody

ABP53838-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53839-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP57354-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

Anti-p38 alpha

DB-1039 100 tests
EUR 568.8

Anti-p38 beta

DB-1040 100 tests
EUR 568.8

Anti-p38 gamma

DB-1041 100 tests
EUR 568.8

Anti-p38 delta

DB-1042 100 tests
EUR 568.8

Anti-p38-a

DB-161-0.05 50 μl
EUR 322.8

Anti-p38-a

DB-161-0.1 100 μl
EUR 506.4

Anti-p38-b

DB-162-0.05 50 μl
EUR 322.8

Anti-p38-b

DB-162-0.1 100 μl
EUR 506.4

Anti-p38-g

DB-163-0.05 50 μl
EUR 322.8

Anti-p38-g

DB-163-0.1 100 μl
EUR 506.4

Anti-p38-d

DB-164-0.05 50 μl
EUR 322.8

Anti-p38-d

DB-164-0.1 100 μl
EUR 506.4

Anti-p38 alpha

DB1039 100 tests
EUR 568.8

Anti-p38 beta

DB1040 100 tests
EUR 568.8

Anti-p38 gamma

DB1041 100 tests
EUR 568.8

Anti-p38 delta

DB1042 100 tests
EUR 568.8

AIMP2/p38 Antibody

DF12048 200ul
EUR 420

Crk p38 Antibody

AF6323 200ul
EUR 420

p38 MAPK Antibody

AF6455 200ul
EUR 420

p38 MAPK Antibody

AF6456 200ul
EUR 420

p38 MAPK Antibody

AF6457 200ul
EUR 420

anti- p38 antibody

FNab06076 100µg
EUR 606.3
Description: Antibody raised against p38

p38 Polyclonal Antibody

ES3111-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES3111-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES3112-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES3112-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES8347-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 Polyclonal Antibody

ES8347-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 Polyclonal Antibody

ES4837-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES4837-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES4838-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES4838-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

P38 MAPK antibody

70R-34325 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

70R-34327 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK antibody

70R-33398 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

70R-33400 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK Antibody

49379-100ul 100ul
EUR 399.6

p38 MAPK Antibody

49379-50ul 50ul
EUR 286.8

P38 delta protein

30R-2868 5 ug
EUR 603.6
Description: Purified recombinant Human P38 delta protein

p38 alpha protein

30R-2870 5 ug
EUR 603.6
Description: Purified recombinant Human p38 alpha protein

p38 beta protein

30R-2875 5 ug
EUR 603.6
Description: Purified recombinant Human p38 beta protein

p38 MAPK antibody

20R-2950 100 ul
EUR 471.6
Description: Rabbit polyclonal p38 MAPK antibody

p38 Polyclonal Antibody

41305-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41305-50ul 50ul
EUR 224.4

p38 Polyclonal Antibody

41306-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41306-50ul 50ul
EUR 224.4

p38 MAPK antibody

10R-8422 100 ul
EUR 471.6
Description: Mouse monoclonal p38 MAPK antibody

p38 MAPK antibody

20R-1572 100 ug
EUR 846
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

20R-2087 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2088 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2403 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

p38 Blocking Peptide

20-abx161932
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

p38 (pY323) Antibody

20-abx133058
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p38 (pY182) Antibody

20-abx134951
  • EUR 460.80
  • EUR 727.20
  • EUR 276.00
  • 100 ul
  • 200 ul
  • 30 ul

p38 MAPK Antibody

20-abx012798
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p38 MAPK Antibody

20-abx012875
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p38 (pT180) Antibody

20-abx009863
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p38 Polyclonal Antibody

ABP52112-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52113-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Blocking Peptide

20-abx061736
  • EUR 309.60
  • EUR 460.80
  • 1 mg
  • 5 mg

p38 Blocking Peptide

20-abx062080
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

p38 MAPK Antibody

ABF6456 100 ug
EUR 525.6

p38 MAPK Antibody

abx236077-100ug 100 ug
EUR 577.2

p38 beta, Active

7763-100
EUR 5214

p38 beta, Active

7763-5
EUR 444

Anti-p38 Antibody

A00176 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for p38 Antibody (MAPK14) detection.tested for WB in Human, Mouse, Rat.

anti-p38 MAPK

LF-PA0160 100 ul
EUR 400.8
Description: Rabbit polyclonal to p38 MAPK

Anti-p38 antibody

PAab06076 100 ug
EUR 426

p38 alpha-MAPK14

RA15053 100 ug
EUR 631.2

Anti-p38 antibody

STJ94876 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

Anti-p38 antibody

STJ94877 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

Anti-p38 antibody

STJ94878 200 µl
EUR 236.4
Description: p38 is a protein encoded by the MAPK14 gene which is approximately 41,2 kDa. p38 is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the IL-2 pathway, toll-like receptor signalling pathways, the VEGF signalling pathway and 4-1BB pathway. This protein falls under the MAP kinase family. It acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. p38 is expressed in the brain, heart, placenta, pancreas and skeletal muscle. Mutations in the MAPK14 gene may result in patellar tendinitis and lumbosacral lipoma. STJ94878 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p38 protein.

Anti-p38 antibody

STJ94879 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

Anti-p38 antibody

STJ97615 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

Anti-P38 antibody

STJ98898 200 µl
EUR 236.4
Description: Mouse monoclonal to P38.

Anti-P38 antibody

STJ98899 200 µl
EUR 236.4
Description: Mouse monoclonal to P38.

anti-Crk p38

YF-PA11088 50 ul
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11089 50 ug
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11090 100 ug
EUR 483.6
Description: Rabbit polyclonal to Crk p38

anti-Crk p38

YF-PA23509 50 ul
EUR 400.8
Description: Mouse polyclonal to Crk p38

anti-AIMP2/p38

YF-PA15507 50 ug
EUR 435.6
Description: Mouse polyclonal to AIMP2/p38

Anti-p38 (3D5)

YF-MA12551 200 ul
EUR 435.6
Description: Mouse monoclonal to p38

Anti-p38 (1C9)

YF-MA12552 100 ug
EUR 435.6
Description: Mouse monoclonal to p38

p38 MAPK Antibody

R20266-0.1ML 100ul
EUR 409

Crk Antibody p38

R31526 100 ug
EUR 419

p38 Antibody (MAPK14)

F50496-0.08ML 0.08 ml
EUR 165

p38 Antibody (MAPK14)

F50496-0.4ML 0.4 ml
EUR 379

MM-102 (TFA)

HY-12220A 10mM/1mL
EUR 315.6

BP-1-102

HY-100493 100mg
EUR 1614

Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit

EM1199 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml

Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit

abx197397-96tests 96 tests
EUR 990

p38 MAPK Rabbit pAb

A8038-100ul 100 ul
EUR 369.6

p38 MAPK Rabbit pAb

A8038-200ul 200 ul
EUR 550.8

p38 MAPK Rabbit pAb

A8038-20ul 20 ul Ask for price

p38 MAPK Rabbit pAb

A8038-50ul 50 ul Ask for price

p38 gamma/delta Antibody

DF10341 200ul
EUR 420

p38 MAPK Conjugated Antibody

C49379 100ul
EUR 476.4

p38 MAPK Blocking Peptide

AF6455-BP 1mg
EUR 234

p38 MAPK Blocking Peptide

AF6456-BP 1mg
EUR 234

p38 MAPK Blocking Peptide

AF6457-BP 1mg
EUR 234

p38 Polyclonal Conjugated Antibody

C41305 100ul
EUR 476.4

anti- p38 MAPK antibody

FNab06077 100µg
EUR 606.3
Description: Antibody raised against p38 MAPK

P38 (1G1) Monoclonal Antibody

EM1369-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC

P38 (1G1) Monoclonal Antibody

EM1369-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC

p38 MAPK Polyclonal Antibody

ES8901-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 MAPK Polyclonal Antibody

ES8901-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 MAPK antibody (Thr180)

70R-37313 100 ug
EUR 418.8
Description: Rabbit Polyclonal p38 MAPK antibody (Thr180)

p38 MAPK antibody (Tyr182)

70R-37314 100 ug
EUR 418.8
Description: Rabbit Polyclonal p38 MAPK antibody (Tyr182)

P38 MAPK antibody (Thr179)

70R-34324 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody (Thr179)

P38 MAPK antibody (Tyr182)

70R-34326 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody (Tyr182)

p38 MAPK antibody (Tyr322)

70R-33397 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody (Tyr322)

p38 MAP Kinase antibody

70R-11620 100 ug
EUR 501.6
Description: Rabbit polyclonal p38 MAP Kinase antibody

Phospho-p38 MAPK antibody

70R-11824 100 ug
EUR 630
Description: Rabbit polyclonal Phospho-p38 MAPK antibody

p38 MAPK Rabbit pAb

A11340-100ul 100 ul
EUR 369.6

p38 MAPK Rabbit pAb

A11340-200ul 200 ul
EUR 550.8

p38 MAPK Rabbit pAb

A11340-20ul 20 ul
EUR 219.6

p38 MAPK Rabbit pAb

A11340-50ul 50 ul
EUR 267.6

p38 MAPK Rabbit pAb

A14401-100ul 100 ul
EUR 369.6

p38 MAPK Rabbit pAb

A14401-200ul 200 ul
EUR 550.8

p38 MAPK Rabbit pAb

A14401-20ul 20 ul
EUR 219.6

p38 MAPK Rabbit pAb

A14401-50ul 50 ul
EUR 267.6

p38 MAPK Rabbit pAb

A10832-100ul 100 ul
EUR 460.8

p38 MAPK Rabbit pAb

A10832-200ul 200 ul
EUR 664.8

p38 MAPK Rabbit pAb

A10832-20ul 20 ul
EUR 219.6

p38 MAPK Rabbit pAb

A10832-50ul 50 ul
EUR 318

Phospho-p38 MAPK Antibody

3438-100
EUR 510

p38 MAP Kinase antibody

20R-1458 100 ug
EUR 807.6
Description: Rabbit polyclonal p38 MAP Kinase antibody

p38 MAPK Monoclonal Antibody

27507-100ul 100ul
EUR 302.4

p38 MAPK Monoclonal Antibody

27507-50ul 50ul
EUR 224.4

p38 MAP Kinase Antibody

3114-100
EUR 411.6

p38 MAP Kinase Antibody

3114-30T
EUR 175.2

p38 (pY323) Blocking Peptide

20-abx161669
  • EUR 376.80
  • EUR 610.80
  • 1 mg
  • 5 mg

p38 MAPK Rabbit mAb

A4771 20 μL
EUR 18

p38 (pT180 / Y182) Antibody

20-abx133560
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p38 MAPK (pT180) Antibody

abx011783-100ug 100 ug
EUR 526.8

p38 MAPK (pY182) Antibody

20-abx011784
  • EUR 526.80
  • EUR 109.20
  • EUR 92.40
  • 100 ug
  • 10 ug
  • 5 ug

p38 MAPK (pY322) Antibody

20-abx011785
  • EUR 526.80
  • EUR 109.20
  • 100 ug
  • 10 ug

p38 MAPK Polyclonal Antibody

ABP59793-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein

When the development of the free (PFS) of FGFR4 negative vs positive patients compared to patients scored as positive FGFR4 significantly shortened PFS compared with those who negatively stained. All associations FGFR4 and shortened PFS lost for multivariate testing. No significant association was found in the OS.

April

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