Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

Objective: biomarkers to optimize treatment outcomes with lenvatinib in patients with advanced hepatocellular carcinoma remains to be established though research intensive and comprehensive genome. Lenvatinib characterized by leading potential inhibition of fibroblast growth factor receptor (FGFR) 4 compared with the prior tyrosine kinase inhibitor. Thus, in this study, we focus on simple quantification of FGFR4 in tumor as a potential predictive indicator.


Methods: According to The Cancer Genome Atlas data collection curation, FGFR4 RNA is widely expressed on hepatocellular carcinoma in the absence of changes in genes. Gene set enrichment analysis revealed that tumor aggressiveness was closely tied to the level of FGFR4. To confirm the relationship between the benefits lenvatinib and tumor addiction to FGFR4 pathway, we analyzed the protein levels in tumors and peripheral blood obtained from 57 patients enrolled prospectively treated with lenvatinib.


Results: Positive immunohistochemical (> 10% of tumor cells) of FGFR4 in biopsy samples before treatment was associated with longer progression-free survival (2.5 vs. 5.5 months, P = 0.01) and objective response rate benefit ( 31% vs 81%, P = 0.006). In contrast, soluble FGFR4 concentration in peripheral blood were measured by enzyme-linked ELISA test was not associated with survival results, due to fluctuations that reflect liver fibrosis. Additional analysis of RNA sequencing using archival surgical specimens (n ​​= 90) suggested that alternative RNA splicing of FGFR4 in cancer also may explain this difference.

Tumor <em>Fibroblast</em> <em>Growth</em> <em>Factor</em> Receptor <em>4</em> Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma
Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

mir-7-5p Increase hepatic stellate cells activation by targeting Fibroblasts Growth Factor Receptor 4

Objective: fibroblast growth factor receptor 4 (FGFR4) is a key mediator to protect the liver from chronic injury. MicroRNA-7 (miR-7) is a tumor suppressor and associated with lipid homeostasis in the liver. This study was designed to examine the role of miR-7-5p / FGFR4 axis in liver fibrogenesis.


Methods:
TargetScan employed to predict microRNAs target FGFR4 in the 3′-translated region (3′-UTR). mir-7-5p and FGFR4 expression in liver tissue pathological and LX-2 cells was determined by using qRT-PCR and immunoblotting test. A dual-luciferase test performed to validate the prediction target. A Cell Counting Lit-8 assay was performed to assess the ability of the proliferation of LX-2 cells. Hydroxyproline content in LX-2 cells was measured using the test tool hidroksiprolin. Expression of liver stellate cells (HSC) activation markers examined using qRT-PCR and immunoblotting test.


Results: FGFR4 is suspected targets of miR-7-5p. In the LX-2 cells, miR-7-5p targeted to FGFR4 to bind a 3′-UTR. FGFR4 was downregulated, but miR-7-5p is markedly improved in the sample of the liver as liver fibrosis level rise. mir-7-5p negatively associated with FGFR4 expression in the liver tissue. Inhibitor of miR-7-5p blocked lipopolysaccharide-induced proliferation and activation of LX-2 cells, and FGFR4 LX-2 inhibits excessive cell proliferation and activation induced by miR-7-5p.


Conclusion: miR-7-5p promote HSC proliferation and activation by downregulating FGFR4. Syndecan-4 is a member of the syndecan family of transmembrane heparan sulfate proteoglycans, and is involved in cell protection, proliferation, and coagulation-fibrinolytic system of blood in vascular endothelial cells. heparan sulfate chains allows the fibroblast growth factor-2 (FGF-2) to form a complex with the receptor and transduce signals for cell growth.

p38 Antibody

20-abx141038
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

20-abx133223
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

p38 antibody

70R-51505 100 ul
EUR 321.6
Description: Purified Polyclonal p38 antibody

p38 antibody

70R-51506 100 ul
EUR 344.4
Description: Purified Polyclonal p38 antibody

p38 Antibody

35478-100ul 100ul
EUR 468

p38 Antibody

48644-100ul 100ul
EUR 399.6

p38 Antibody

48644-50ul 50ul
EUR 286.8

p38 Antibody

20-abx007541
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

E38PA7126 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA3186 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA4721 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA5060 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA5094 100ul
EUR 225
Description: Available in various conjugation types.

SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor

E1B1863 1mg
EUR 193.2

p38 Mouse mAb

E2220879 100ul
EUR 225
Description: Available in various conjugation types.

anti-Crk p38

YF-PA23509 50 ul
EUR 400.8
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11088 50 ul
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11089 50 ug
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11090 100 ug
EUR 483.6
Description: Rabbit polyclonal to Crk p38

p38 Rabbit pAb

E2340697 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2380881 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2381051 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2251338 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2251719 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit mAb

E2R25239 100μl
EUR 225
Description: Available in various conjugation types.

p38 Rabbit mAb

E2R27123 100μl
EUR 225
Description: Available in various conjugation types.

p38 beta, Active

7763-100 each
EUR 5214

p38 beta, Active

7763-5 each
EUR 444

p38 beta protein

30R-2875 5 ug
EUR 603.6
Description: Purified recombinant Human p38 beta protein

anti-AIMP2/p38

YF-PA15507 50 ug
EUR 435.6
Description: Mouse polyclonal to AIMP2/p38

Crk p38 Antibody

AF6323 100ul
EUR 280
Description: Human,Mouse,Rat,Monkey

Crk Antibody p38

R31526 100 ug
EUR 356.15
Description: CRK, also known as p38, is a protein that in humans is encoded by the CRK gene. This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It is mapped to 17p13.3. The protein participates in the Reelin signaling cascade downstream of DAB1. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of Crk functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Crk p38 Antibody

AF6323-100ul 100ul
EUR 280

Crk p38 Antibody

AF6323-200ul 200ul
EUR 350

p38 MAPK Antibody

abx236077-100ug 100 ug
EUR 577.2

p38 MAPK antibody

10R-8422 100 ul
EUR 471.6
Description: Mouse monoclonal p38 MAPK antibody

P38 MAPK antibody

20R-2403 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK antibody

20R-2950 100 ul
EUR 471.6
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

20R-1572 100 ug
EUR 846
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

20R-2087 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2088 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 delta protein

30R-2868 5 ug
EUR 603.6
Description: Purified recombinant Human P38 delta protein

p38 alpha protein

30R-2870 5 ug
EUR 603.6
Description: Purified recombinant Human p38 alpha protein

p38 MAPK Antibody

49379-100ul 100ul
EUR 399.6

p38 MAPK Antibody

49379-50ul 50ul
EUR 286.8

p38 MAPK antibody

70R-33398 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

70R-33400 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

70R-34325 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

70R-34327 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK Antibody

ABF6456 100 ug
EUR 525.6

p38 MAPK Antibody

20-abx012875
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p38 MAPK Antibody

20-abx012798
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

anti- p38 antibody

FNab06076 100µg
EUR 606.3
Description: Antibody raised against p38

p38 MAPK Antibody

AF6455 100ul
EUR 280
Description: Human,Mouse,Rat,Pig,Monkey

p38 MAPK Antibody

AF6456 100ul
EUR 280
Description: Human,Mouse,Rat,Pig

p38 MAPK Antibody

AF6457 100ul
EUR 280
Description: Human,Mouse

p38 MAPK Antibody

R20266-0.1ML 100ul
EUR 347.65
Description: This recombinant p38 antibody reacts to human p38 MAPK. It may also react to the rat and mouse protein, as predicted by immunogen homology.

p38 MAPK Antibody

E2310008 100ug
EUR 225
Description: Available in various conjugation types.

p38 MAPK Antibody

AF6455-100ul 100ul
EUR 280

p38 MAPK Antibody

AF6455-200ul 200ul
EUR 350

p38 MAPK Antibody

AF6456-100ul 100ul
EUR 280

p38 MAPK Antibody

AF6456-200ul 200ul
EUR 350

p38 MAPK Antibody

AF6457-100ul 100ul
EUR 280

p38 MAPK Antibody

AF6457-200ul 200ul
EUR 350

p38 MAPK Antibody

E18-6456-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

p38 MAPK Antibody

E18-6456-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

p38 (pY182) Antibody

20-abx134951
  • EUR 460.80
  • EUR 727.20
  • EUR 276.00
  • 100 ul
  • 200 ul
  • 30 ul

p38 (pY323) Antibody

20-abx133058
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p38 (pT180) Antibody

20-abx009863
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

AIMP2/p38 Antibody

DF12048 100ul
EUR 280
Description: Human,Mouse,Rat

p38 alpha-MAPK14

RA15053 100 ug
EUR 631.2

p38 (pY182) Antibody

E38PA7040 100ul
EUR 225
Description: Available in various conjugation types.

p38 (pT180) Antibody

E38PA3187 100ul
EUR 225
Description: Available in various conjugation types.

p38 (pY323) Antibody

E38PA4458 100ul
EUR 225
Description: Available in various conjugation types.

AIMP2/p38 Antibody

DF12048-100ul 100ul
EUR 280

AIMP2/p38 Antibody

DF12048-200ul 200ul
EUR 350

p38 MAPK Inhibitor

T36010-10mg 10mg Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-1g 1g Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-1mg 1mg Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-50mg 50mg Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-5mg 5mg Ask for price
Description: p38 MAPK Inhibitor

p38 Antibody (MAPK14)

F50496-0.08ML 0.08 ml
EUR 140.25
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

p38 Antibody (MAPK14)

F50496-0.4ML 0.4 ml
EUR 322.15
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

p38 Blocking Peptide

20-abx061736
  • EUR 309.60
  • EUR 460.80
  • 1 mg
  • 5 mg

p38 Blocking Peptide

20-abx062080
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

p38 Blocking Peptide

20-abx161932
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

Human p38 MAPK alpha ,pT180/Y182(p38 MAPKP) Elisa Kit

EK715654 96 Wells
EUR 0.51

p38 Polyclonal Antibody

41305-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41305-50ul 50ul
EUR 224.4

p38 Polyclonal Antibody

41306-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41306-50ul 50ul
EUR 224.4

p38 Polyclonal Antibody

ABP52112-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52113-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP53838-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53839-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP57354-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ES4837-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES4837-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES4838-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES4838-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES3111-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES3111-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES3112-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES3112-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES8347-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 Polyclonal Antibody

ES8347-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 Polyclonal Antibody

ABP0150-100uL 100 μL
EUR 229
Description: Rabbit Anti-p38 Polyclonal Antibody

p38 Polyclonal Antibody

E041305 100μg/100μl
EUR 255
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E041306 100μg/100μl
EUR 255
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-75662 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73511 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73512 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73513 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73514 100ug
EUR 225
Description: Available in various conjugation types.

P38 (411 - 425), M. leprae

5-01677 4 x 1mg Ask for price

Rat P38 Mitogen-activated Protein Kinase (p38 MAPK) Elisa Kit

EK721153 96 Wells
EUR 0.63

Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit

abx197397-96tests 96 tests
EUR 990

Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit

EM1199 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml

Human P38 Mitogen-activated Protein Kinase (p38 MAPK) Elisa Kit

EK713067 96 Wells
EUR 0.32

p38 MAPK-IN-2

HY-U00324 10mg
EUR 4440

p38 MAPK-IN-1

HY-12839 5mg
EUR 639.6

p38 MAPK-IN-2

T11241-10mg 10mg Ask for price
Description: p38 MAPK-IN-2

p38 MAPK-IN-2

T11241-1g 1g Ask for price
Description: p38 MAPK-IN-2

p38 MAPK-IN-2

T11241-1mg 1mg Ask for price
Description: p38 MAPK-IN-2

p38 MAPK-IN-2

T11241-50mg 50mg Ask for price
Description: p38 MAPK-IN-2

p38 MAPK-IN-2

T11241-5mg 5mg Ask for price
Description: p38 MAPK-IN-2

p38 MAPK-IN-1

T16424-10mg 10mg Ask for price
Description: p38 MAPK-IN-1

p38 MAPK-IN-1

T16424-1g 1g Ask for price
Description: p38 MAPK-IN-1

p38 MAPK-IN-1

T16424-1mg 1mg Ask for price
Description: p38 MAPK-IN-1

p38 MAPK-IN-1

T16424-50mg 50mg Ask for price
Description: p38 MAPK-IN-1

p38 MAPK-IN-1

T16424-5mg 5mg Ask for price
Description: p38 MAPK-IN-1

P38 Mouse mAb (6F5)

E2250381 100ul
EUR 225
Description: Available in various conjugation types.

P38 Mouse mAb (8B3)

E2250382 100ul
EUR 225
Description: Available in various conjugation types.

p38 MAPK-IN-3

T61803-10mg 10mg Ask for price
Description: p38 MAPK-IN-3

p38 MAPK-IN-3

T61803-1g 1g Ask for price
Description: p38 MAPK-IN-3

p38 MAPK-IN-3

T61803-1mg 1mg Ask for price
Description: p38 MAPK-IN-3

p38 MAPK-IN-3

T61803-50mg 50mg Ask for price
Description: p38 MAPK-IN-3

p38 MAPK-IN-3

T61803-5mg 5mg Ask for price
Description: p38 MAPK-IN-3

p38-α MAPK-IN-1

HY-18874 100mg
EUR 3531.6

p38-α MAPK-IN-1

T12347-10mg 10mg Ask for price
Description: p38-α MAPK-IN-1

p38-α MAPK-IN-1

T12347-1g 1g Ask for price
Description: p38-α MAPK-IN-1

p38-α MAPK-IN-1

T12347-1mg 1mg Ask for price
Description: p38-α MAPK-IN-1

p38-α MAPK-IN-1

T12347-50mg 50mg Ask for price
Description: p38-α MAPK-IN-1

p38-α MAPK-IN-1

T12347-5mg 5mg Ask for price
Description: p38-α MAPK-IN-1

p38-α MAPK-IN-4

T61091-10mg 10mg Ask for price
Description: p38-α MAPK-IN-4

p38-α MAPK-IN-4

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Description: p38-α MAPK-IN-4

p38-α MAPK-IN-4

T61091-1mg 1mg Ask for price
Description: p38-α MAPK-IN-4

p38-α MAPK-IN-4

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Description: p38-α MAPK-IN-4

p38-α MAPK-IN-4

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Description: p38-α MAPK-IN-4

In this study, cows were cultured aortic endothelial cells, and intracellular signaling pathways that mediate the regulation of syndecan-4 expression in dense and sparse culture by FGF-2 were analyzed.

April

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